What are symptoms of cholinesterase inhibition?

Cholinesterase inhibition occurs when the enzyme cholinesterase, which is responsible for breaking down the neurotransmitter acetylcholine in the body, is inhibited. As a result, there is an accumulation of acetylcholine at synapses, leading to overstimulation of the nervous system. Symptoms related to cholinesterase inhibition can include muscle twitching, difficulty breathing, and neurological effects, such as damage to the nerves and overall nervous system function.

This condition can occur due to certain pesticides, particularly organophosphates and carbamates, which are designed to interfere with the normal functioning of the enzyme. Therefore, the correct response highlights the negative impact on nerves and the nervous system, which aligns with the physiological effects seen in cases of cholinesterase inhibition.